During administration of doxorubicin, the nurse notices a red streak forming along the vein and suspects a flare reaction. After stopping the IV push, the nurse verifies blood return and slowly pushes normal saline. The flare reaction subsides, and the nurse resumes the administration. Which drug may be ordered with the next cycle to help prevent another flare reaction?
A. Acetaminophen
B. An antihistamine
C. Ibuprofen
D. An anti-inflammatory
